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Research project

TISuMR: Integrated Tissue Slice Culture and NMR Metabolomics – A Novel Approach Towards Systemic

Project overview

This international collaboration, led by Southampton, aims to provide a radically new technological platform for the integrated culture and NMR observation of liver tissue slices, with the immediate objective to elucidate the mechanism of liver damage by cholestasis.

Staff

Lead researchers

Professor Marcel Utz

Professorial Fellow-Research
Research interests
  • Integration of microfluidic lab-on-a-chip technology with NMR spectroscopy and imaging;
  • Behaviour of complex materials.
Connect with Marcel

Email: Marcel.Utz@soton.ac.uk

Research outputs

Marek Plata, Manvendra Sharma, Marcel Utz & Jörn M. Werner, 2022, Journal of the American Chemical Society, 145(5), 3204–3210
DOI:
Type: article
Bishnubrata Patra, Manvendra Sharma, William G Hale & Marcel Utz, 2021, Scientific Reports, 11(1)
DOI:
Type: article
James Eills, William G Hale & Marcel Utz, 2021, Progress in Nuclear Magnetic Resonance Spectroscopy
DOI:
Type: review
Marek Plata, William G Hale, Manvendra Sharma, Jorn Werner & Marcel Utz, 2021, Lab on a Chip, 21(8), 1598-1603
DOI:
Type: article
Yibin Sun, Hongxun Fang, Xujing Lin, Xiuxiu Wang, Ganyu Chen, Xinchang Wang, Zhongqun Tian, Liulin Yang, Marcel Utz & Xiaoyu Cao, 2021, Chemistry, 2021(3), 948–956
DOI:
Type: article
Vincent Moxley-Paquette, Daniel Lane, Ronald Soong, Paris Ning, Monica Bastawrous, Bing Wu, Maysam Zamani Pedram, Md Aminul Haque Talukder, Ebrahim Ghafar-Zadeh, Dimitri Zverev, Richard Martin, Bob Macpherson, Mike Vargas, Daniel Schmidig, Stefan Graf, Thomas Frei, Danijela Al Adwan-Stojilkovic, Peter De Castro, Falko Busse, Wolfgang Bermel, Till Kuehn, Rainer Kuemmerle, Michael Fey, Frank Decker, Henry Stronks, Ruby May A. Sullan, Marcel Utz & André J. Simpson, 2020, Analytical Chemistry
DOI:
Type: article
Manvendra Sharma & Marcel Utz, 2019, Journal of Magnetic Resonance, 303, 75-81
DOI:
Type: article